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Archives of Clinical Neuropsychology Advance Access originally published online on September 18, 2009
Archives of Clinical Neuropsychology 2009 24(7):699-709; doi:10.1093/arclin/acp064
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© The Author 2009. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org.

Predictors of Health Status in Nondepressed and Nondemented Individuals with Parkinson's Disease

Dawn M. Schiehsera,b, S. Duke Hanc,d, Stephanie Lessigb,e, David D. Songb,e, Vanessa Zizakb and J. Vincent Filoteoa,b,*

a Department of Psychiatry, UCSD, San Diego, CA, USA
b VA San Diego Healthcare System, San Diego, CA, USA
c Department of Psychology, Loyola University Chicago, Chicago, IL, USA
d Department of Behavioral Sciences, Rush University Medical Center, Chicago, IL, USA
e Department of Neurosciences, UCSD, San Diego, CA, USA

* Corresponding author at: Psychology Service 116B, Veterans Administration San Diego Healthcare System, 3350 La Jolla Village Drive, San Diego, CA 92161, USA. Tel: +1-858-642-1122; fax: +1-858-642-3023. E-mail address: vfiloteo{at}ucsd.edu ( J.V. Filoteo).


  Abstract

Recent studies have shown that self-perceived health status (HS) in Parkinson's disease (PD) is associated with motor, cognitive, or mood symptoms, with the greatest association typically occurring with mood. The purpose of this study was to determine if these associations are present in nondepressed and nondemented individuals with PD by using sensitive neuropsychological measures and statistically derived factors from mood and motor scales. The best predictors of poor HS in PD participants (N = 32) without dementia or depression were mood symptoms, specific to self-reported cognitive impairment and anxiety. Bivariate correlations between HS and number of correct categories on the Wisconsin Card Sorting Test and the gait–balance factor from the Unified Parkinson's Disease Rating Scale Part III were also significant or approached significance. These findings suggest that specific mood and cognitive symptoms continue to be important factors in HS in those individuals who lack clinical levels of depression or dementia.

Keywords Parkinson's disease; Health status; Health-related quality of life; Quality of life

Accepted: August 17, 2009


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