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Archives of Clinical Neuropsychology Advance Access published online on March 25, 2009
Archives of Clinical Neuropsychology, doi:10.1093/arclin/acp010
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© The Author 2009. Published by Oxford University Press on behalf of the National Academy of Neuropsychology. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org.

Validity of the CogState Brief Battery: Relationship to Standardized Tests and Sensitivity to Cognitive Impairment in Mild Traumatic Brain Injury, Schizophrenia, and AIDS Dementia Complex

Paul Maruffa,b,*, Elizabeth Thomasc, Lucette Cysiqued,e, Bruce Brewe, Alex Collieb, Peter Snyderf and Robert H. Pietrzakg

a CogState Ltd., Melbourne, Australia
b Centre for Neuroscience, University of Melbourne, Parkville, Australia
c School of Behavioral Science, University of Melbourne, Parkville, Australia
d Department of Psychiatry, University of California at San Diego, San Diego, CA, USA
e Department of Neurology, St Vincent's Hospital, University of New South Wales, Sydney, Australia
f Department of Clinical Neurosciences, Warren Alpert Medical School of Brown University, Providence, RI, USA
g Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA

* Corresponding author at: CogState Ltd., 7/21 Victoria Street, Melbourne 3000, Australia. Tel.: +61-396-641-300; fax: +61-396-641-301. E-mail address: pmaruff{at}cogstate.com (P. Maruff).


  Abstract

This study examined the validity of the four standard psychological paradigms that have been operationally defined within the CogState brief computerized cognitive assessment battery. Construct validity was determined in a large group of healthy adults. CogState measures of processing speed, attention, working memory, and learning showed strong correlations with conventional neuropsychological measures of these same constructs (r's = .49 to .83). Criterion validity was determined by examining patterns of performance on the CogState tasks in groups of individuals with mild head injury, schizophrenia, and AIDS dementia complex. Each of these groups was impaired on the CogState performance measures (Cohen's d's = –.60 to –1.80) and the magnitude and nature of this impairment was qualitatively and quantitatively similar in each group. Taken together, the results suggest that the cognitive paradigms operationally defined in the CogState brief battery have acceptable construct and criterion validity in a neuropsychological context.

Keywords Computer cognitive; Assessment; Neuropsychiatric

Accepted: November 26, 2008


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